Frits & Filters

Frits are friction fitted within the cartridge to retain the sorbent, and can also perform a variety of filtration functions.

Solid Phase Extraction Frits and Filters

Frits are friction fitted within the cartridge to retain the sorbent, and also to perform a variety of filtration functions. Applied Separations’ porous plastic frits are naturally hydrophobic, but aqueous solutions can be forced through under pressure. If gravity flow of an aqueous solution is desired, then select a specially treated polyethylene hydrophilic frit.

Other frits are also available upon request, please contact us to discuss your requirements.


Polyethylene hydrophobic frits

Polyethylene hydrophobic frits are the standard and are used in most commercial SPE products. They are also used with non-aqueous solutions such as solvents, alcohols, acids, bases, halogenated and aromatic hydrocarbons and ketones. These hydrophobic frits can be wetted with organic solvents.

Size Quantity 20µ 70µ 100µ
1mL (6.1mm) 100 2421 2493 2952
3mL (9.4mm) 100 2423 2494 2953
6mL (13.3mm) 100 2426 2495 2954
12mL (16.1mm) 100 2488 2430 2955
35mL (24.0mm) 100 2431 2496 2956
60mL (27.1mm) 100 2489 2469 2957
Mini (10.0mm) 100 2491 2468 2958
500mg LRC (9.4mm) 100 2451 2425 2960

Polyethylene hydrophilic frits

Polyethylene hydrophilic frits are used for general filtration and as clarifications of aqueous solutions and certain other solutions. These hydrophilic frits are specially treated and can consequently be wetted with aqueous solutions. This frit is ideal for gravity flow of an aqueous solution.

Size Quantity 20µ 70µ 100µ
1mL (6.1mm) 100 2961 2970 2979
3mL (9.4mm) 100 2962 2971 2980
6mL (13.3mm) 100 2963 2972 2981
12mL (16.1mm) 100 2964 2973 2982
35mL (24.0mm) 100 2965 2974 2983
60mL (27.1mm) 100 2966 2975 2984
Mini (10.0mm) 100 2967 2976 2985
500mg LRC (9.4mm) 100 2969 2978 2987

PTFE frits

PTFE frits can be used to filter almost any organic solvent. They are used for trace analysis and high sensitivity work with solvent detection systems which are not compatible with polyethylene or polypropylene frits. PTFE is a hydrophobic membrane, resistant to most organic solvents, acids, and bases.

Size Quantity
1mL (6.1mm) 100 2499
3mL (9.4mm) 100 2901
6mL (13.3mm) 100 2902
12mL (16.1mm) 100 2903
35mL (24.0mm) 100 2904
60mL (27.1mm) 100 2905
Mini (10.0mm) 100 2906
500mg LRC (9.4mm) 100 2908

Polypropylene frits

Polypropylene frits are hydrophobic and are best used for low extractables. Polypropylene frits are similar to PTFE frits in their filtration behaviour and serve as an economical alternative to the more expensive PTFE frits.

Size Quantity 150µ
1mL (6.1mm) 100 2988
3mL (9.4mm) 100 2989
6mL (13.3mm) 100 2990
12mL (16.1mm) 100 2991
35mL (24.0mm) 100 2992
60mL (27.1mm) 100 2993
Mini (10.0mm) 100 2994
500mg LRC (9.4mm) 100 2996

Note: Most commercial SPE suppliers use hydrophobic polyethylene 20µ frits.

  • Choose another to control flow rate.
  • Larger pore frits are typically used for gravity elution.


To request more information on Applied Separations range of SPE cartridges and accessories, please send us a message and we will be in touch as soon as possible.